Better Therapies For Cardiovascular Disease May Be Product Of Protein Tug Of War

Two proteins are in a tug of war that determines how much the body makes of superoxide, a highly reactive and potentially destructive product of oxygen that's dramatically elevated in cardiovascular disease, researchers report.Their finding indicates an antiulcer drug just may help the body reduce...

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Link Between Vitamin D Deficiency And Type 1 Diabetes

A study led by researchers from the University of California, San Diego School of Medicine has found a correlation between vitamin D3 serum levels and subsequent incidence of Type 1 diabetes. The six-year study of blood levels of nearly 2,000 individuals suggests a preventive role for vitamin D3 in...

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Passive Smoking Tied To Type 2 Diabetes, Obesity

If you need another reason to steer clear of cigarette smoke, consider this: a new study presented at a conference this week suggests breathing in secondhand smoke is linked to higher risks of developing type 2 diabetes and obesity.Presented on Sunday at The Endocrine Society's 94th Annual Meeting in Houston, the findings show that adults exposed to secondhand smoke have higher rates of these diseases...

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Long Term Insulin Not Linked To Higher Risk Of Heart Attack, Stroke, Cancer

Long term use of insulin does not put people with diabetes or pre-diabetes at higher risk for heart attack, stroke or cancer, according to a large international study that followed more than 12,500 people in 40 countries over 6 years.One of the study's two principal investigators, Dr Hertzel Gerstein, of McMaster University in Canada, presented the findings on Monday at the 72nd scientific sessions...

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Waist Size, Regardless Of BMI, Linked To Diabetes Risk

Waist circumference is strongly and independently linked to diabetes type two risk, even after accounting for body mass index (BMI), and should be measured more widely for estimating risk, researchers from the Medical Research Council (MRC) Epidemiology Unit, UK, reported in PLoS Medicine. The authors...

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Lower Limb Amputation Rates Associated With Diabetes Drop, US

An investigation by the Centers for Disease Control and Prevention, found that between 1996 and 2008, the number of leg and foot amputations among U.S. individuals, aged 40+ with diagnosed diabetes, decreased by 65%.The study, entitled "Declining Rates of Hospitalization for Non-traumatic Lower-Extremity Amputation in the Diabetic Population Aged 40 years or Older: U.S., 1988-2008," is published online...

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American Diet Fuelling Heart Disease And Diabetes Rates In Southeast Asia

As Southeast Asians embrace American fast foods, such as pizza, french fries, hot dogs and hamburgers, more are dying prematurely form coronary heart disease and developing diabetes type 2, researchers from the University of Minnesota School of Public Health and the National University of Singapore reported in the journal Circulation. The authors say that attention should be focused on the impact...

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Adult Stem Cells From Bone Marrow

Researchers from the University of Maryland School of Maryland report promising results from using adult stem cells from bone marrow in mice to help create tissue cells of other organs, such as the heart, brain and pancreas - a scientific step they hope may lead to potential new ways to replace cells lost in diseases such as diabetes, Parkinson's or Alzheimer's. The research in collaboration with...

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Does Psoriasis Increase Type 2 Diabetes Risk?

Two to four percent of adults suffer from psoriasis, a common chronic inflammatory disease, in which the irritated skin becomes red and flaky with silver-white scales. A new UK study, published Online First in JAMA's Archives of Dermatology, has now revealed that psoriasis could be a potential risk factor for developing type 2 diabetes mellitus (T2DM).Rahat S. Azfar, M.D. from Philadelphia's University...

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Fructose In Moderation Could Be Beneficial For Diabetics

A new study by researchers at St. Michael's Hospital suggests that fructose may not be as bad for us as previously thought and that it may even provide some benefit."Over the last decade, there have been connections made between fructose intake and rates of obesity," said Dr. John Sievenpiper, a senior author of the study. "However, this research suggests that the problem is likely one of overconsumption,...

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Gene May Link Diabetes and Alzheimer's

  In recent years it became clear that people with diabetes face an ominous prospect -- a far greater risk of developing Alzheimer's disease. Now researchers at The City College of New York (CCNY) have shed light on one reason why. Biology Professor Chris Li and her colleagues have discovered...

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Animal Model For Xenotransplantation As A Therapy For Type 1 Diabetes

Type1 diabetes is caused by autoimmune destruction of the insulin-producing beta cells. Over 250,000 patients suffer from type 1 diabetes in Germany who are treated with daily insulin injections to maintain glucose metabolism. Replacement of the destroyed beta cells by transplantation of either a complete pancreas organ or isolated human beta cells is the only effective way to cure the disease. However,...

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Two Takeda Diabetes Drug Applications, FDA Asks For More Info

Takeda says it has received a complete response letter from the FDA regarding NDAs (new drug applications) for alogliptin and fixed-dose combination alogliptin and pioglitazone - both diabetes type 2 investigational therapies. Takeda says it has recently been providing the FDA (Food and Drug Administration) with post marketing data from markets outside the USA. Takeda believes it can provide the additional...

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TSA destroys Teen’s Insulin Pump

Savannah Barry, a 16-year-old diabetic, is criticizing the TSA after an agent incorrectly instructed her to walk through a metal detector despite the fact she was wearing an expensive insulin pump. The pump stopped working shortly after the security check. The TSA website...

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TSA destroys Teen’s Insulin Pump

Savannah Barry, a 16-year-old diabetic, is criticizing the TSA after an agent incorrectly instructed her to walk through a metal detector despite the fact she was wearing an expensive insulin pump. The pump stopped working shortly after the security check. The TSA website...

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Doubts Over Long Term Impact Of Group Education For Diabetes Patients

A study published in BMJ (British Medical Journal) states that there are no long term benefits from type 2 diabetes group education programs that only take place once.Type 2 diabetes, a chronic disease which can lead to amputation, loss of vision, kidney failure and many other health problems, requires a person to be extremely vigilant in caring for themselves when it comes to medication, treatment...

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Building Muscle Without Heavy Weights

Weight training at a lower intensity but with more repetitions may be as effective for building muscle as lifting heavy weights says a new opinion piece in Applied Physiology, Nutrition, and Metabolism."The perspective provided in this review highlights that other resistance protocols, beyond the often discussed high-intensity training, can be effective in stimulating a muscle building response that...

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Beta cell stress may trigger development of type 1 diabetes

Scientists have found that a specific type of cellular stress takes place in pancreatic betacells before the onset of type 1 diabetes. In type 1 diabetes (T1D), pancreatic beta cells die from a misguided autoimmune attack, but how and why that happens is still unclear. Now, the JDRF-funded scientists from the Indiana University School of Medicine believe that this stress response in the beta cell...

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Decaffeinated Coffee Preserves Memory Function by Improving Brain Energy Metabolism

Researchers from Mount Sinai School of Medicine have discovered that decaffeinated coffee may improve brain energy metabolism associated with type 2 diabetes. This brain dysfunction is a known risk factor for dementia and other neurodegenerative disorders like Alzheimer's disease. The research is published online in Nutritional Neuroscience. A research group led by Giulio Maria Pasinetti, MD, PhD,...

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Bold new avenue for type 1 diabetes research

Researchers from the University of Pittsburgh have discovered new ways to grow human beta cells in the laboratory. The researchers were able to induce the cells to divide and, notably, to stop the cells from dividing as well.The cell division was achieved by adding the genes ‘cdk’ and ‘cyclin d’ into the beta cells. The way the genes were introduced into the beta cells was via a virus which was able...

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