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Two to four percent of adults suffer from psoriasis, a common chronic inflammatory disease, in which the irritated skin becomes red and flaky with silver-white scales. A new UK study, published Online First in JAMA's Archives of Dermatology, has now revealed that psoriasis could be a potential risk factor for developing type 2 diabetes mellitus (T2DM).
Rahat S. Azfar, M.D. from Philadelphia's University of Pennsylvania, and his team obtained data from The Health Improvement Network (THIN) to evaluate the risk of T2DM in 108,132 people with psoriasis, compared with 430,716 participants without psoriasis, aged between 18 to 90 years.
The researchers state:
"The adjusted attributable risk of developing T2DM among 1,000 patients with psoriasis per year is 0.9 extra cases overall, 0.7 cases in those with mild psoriasis, and 3.0 cases in those with severe psoriasis."
The population-based study also wanted to determine whether those with diabetes and psoriasis were more likely to be prescribed diabetic treatments in comparison with those who had DM but no psoriasis.
They declare: "We observed no difference in use of oral hypoglycemic agents or insulin among patients with mild psoriasis; however, patients with severe psoriasis were more likely to be prescribed oral hypoglycemic agents and had a trend toward being more likely to be prescribed insulin."
we saw a case of psoriasis and type 2DM the latter well controlled by antihyperglycaemic tablet , suffered of high blood pressure , and TIA . His family history remarkable the same story .His mother have DM , also his aunt from his mother side has psoriasis. His father has high blood pressure ,collectively the patient inherit all these chronic disease . what is the underlying mechanism needs team opinion .
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